Background
Centre for Rheumatic Diseases is involved in Ayurveda
research since a decade. Experiences of several drugs
trials initiated study of various clinical research
methods suitable to principles of Ayurveda. CSIR-NMITLI
drug development program added to our learning as
we studied several clinical and diagnostic variables
of Ayurveda and their relation with conventional efficacy
parameters.
The NMITLI data supported our conceptual studies and
we have proposed a vision and method to demonstrate
‘equivalence efficacy and superior safety’
for Ayurveda using Osteoarthritis and Rheumatoid Arthritis
as models. We actually practiced the learning in NMITLI
and successfully completed trial of equivalence to
demonstrate equivalent efficacy of Ayurveda drugs
in randomized double blind multicentric trial.
After NMITLI program, we continued discussion and
study of research methods and their relevance to Ayurveda,
which is key are for any Ayurveda based clinical research.
The efforts from 2002 naturally led to formation of
Research Methodology Group (RMG).
Vision and Objectives
Research Methodology Group is non-profit, academic
platform involving physicians, experts and scientists
for research on ‘Research Methodology’.
The objective of this group is to study research methods
and designs and their appropriateness for various
research questions. We aim to provide methodological
support for Ayurveda and Complementary Medicine related
research.
RMG is contributing for development of Ayurveda –
Modern Medicine Interface for research through meticulous
studies.
Ongoing Projects and Activities
RMG is involved in various activities related to studies,
data generation and publications. Key ongoing activities
of RMG are:
1. Methods to study ‘equivalence
efficacy and superior safety’ in trials
2. Statistical methods for Ayurveda
trials
3. Conceptual study on ‘Safety
Index’ for quantitative evaluation of safety
in clinical trials (a paper)
4. Cochrane review of ‘Ayurveda
interventions for Rheumatoid Arthritis’ (meta-ananlysis
of trials)
5. White Paper on ‘Current Status
and Future Directions of Ayurveda Clinical Research’
(an initiative with Institute of Ayurveda and Integrative
Medicine, Bangalore)
Brief info:
Dr Girish Tillu (M.D., Ayurveda), has worked as
senior research fellow in Interdisciplinary School
of Health Sciences under CSIR - New Millenium
Indian Technology Leadership Initiative program
for Ayurveda based drug development for Arthritis.
Girish is associated with Research Methodology
Group, Centre for Rheumatic Diseases, Pune and
Institute for Ayurveda and Integrative Medicine
for development of research methods and reporting
standards suitable for Ayurveda.
He is Group Leader in Centre for Development of
Advanced Computing, (C-DAC) Pune, and working
on R&D projects in 'Informatics and Integrative
Medicine' domain.
His area of work includes Rheumatology, metabolic
diseases, research methodology for clinical research,
Ayurveda and Informatics.
Contact Details: gtillu@rediffmail.com,
gtillu@gmail.com
Mobile no: +919850026597
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